Search results for "Process variable"
showing 2 items of 2 documents
An oxygen monitoring and control system inside a malaxation machine to improve extra virgin olive oil quality
2013
In recent years, oxygen content regulation during malaxation has been noted as a process parameter. The aim of this study was to identify the optimal time during the malaxation process of the olives of the Sicilian cultivar Nocellara del Belice when the presence of oxygen in the machine headspace activates the enzyme complex in favour of the volatile compounds, without compromising the phenolic composition. During the malaxation process, the atmosphere inside the malaxation machine was modified by blowing pure oxygen from cylinders at specific stages of the process (i.e., 5, 15, 25, and 35 min after the start of malaxation), using a system that allows the automatic and continuous maintenanc…
Relevance of air-to-liquid mass ratio effect on final granule properties of an Enalapril maleate formulation.
2011
In the production of enalapril maleate tablets, the granulation process is the most crucial step. Numerous variables are known to influence the fluid bed granulation process and thus the final granule quality. In this study a novel descriptor for the nozzle parameter "air-to-liquid mass ratio" is presented. Granules manufacturing processes were designed by application of statistical experimental design.The influence of the critical process parameter (CPP)--air-to-liquid mass ratio--on pharmaceutic properties of granules was studied. Air-to-liquid mass ratio can be considered as important variable influencing the droplet size of atomized liquid binder solution.A significant influence of air-…